O Brother, Where Art Thou? is the Coen Brothers’ adaptation of Homer’s The Odyssey, set in rural Mississippi in the 1930s. Three convicts escape and encounter a variety of obstacles on their way home, including sirens, a Cyclops and the Ku Klux Klan. The movie stars George Clooney, John Turturro, Tim Blake Nelson, John Goodman and Holly Hunter.
Filmed In: Canton, Jackson, Oxford, Valley Park, Vicksburg, and Yazoo City, Mississippi. Additional scenes filmed in Santa Clarita and Los Angeles, California.
If You Like: Ocean’s Eleven, Raising Arizona
The last scene in Oh Brother Where Art Thou was filmed in Edwards, MS on the railroad below the Pennebaker house